8/26/2023 0 Comments Psa reliability and validity![]() ![]() ![]() The PSA test measures the level of PSA in a man’s blood. Prostate specific antigen (PSA) is a protein produced by normal as well as malignant cells of the prostate gland and is found in the blood. This is now coming into question more and more as men live longer and many of those men are still healthy and active as they grow older. It’s believed that the harms of screening might outweigh the benefits in an older population. Many guidelines recommend against PSA screening in men older than 70 to 75 years because of the risk of over diagnosis and lack of evidence of a mortality reduction in this age group. Could we be missing cancer in older, healthy men who really need to be treated? Is the cutoff for PSA’s at age 70, still relevant when a significant portion of men may have many years of life ahead of them? This debate has continued for years but one thing that’s certain is that men are living longer. In my area of medicine, there’s the ongoing question of whether men over age 70 should still be screened for prostate cancer with a PSA blood test.
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